Microsoft will warn you if apps could slow down Windows 10
While there's a lot to be said for having certain programs run automatically when you turn on your computer, there is a price to pay. If you have too many apps configured to autorun, you will notice that boot times are increased, and you have to wait longer for your desktop to reach a usable state.
When you install or update software, many will give you a choice of whether to have them run at startup or not, but all too often the choice is made for you. In Windows 10 21H1, Microsoft will start to warn you about new startup entries and give you the chance to take action to avoid system slowdown and slow boot times.